Others titles

  • Substance Registration System
  • UNII Records and Identifications

Keywords

  • FDA Product Code
  • UNII
  • SRS
  • FDA Registration System
  • FDA Database
  • Ingredient Search Results
  • Unique Ingredient Identifier Names
  • Unique Ingredient Identifier Records
  • UNII Descriptive Information
  • Drug Name Dictionary

Unique Ingredient Identifier Records

This dataset contains the details of substances in drugs, biologics, foods and devices registered with a Unique Ingredient Identifier (UNII) through the joint FDA/USP Substance Registration System (SRS).

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John Snow Labs Standard End User License Agreement

Last updated:January 20, 2021

This Standard End User License Agreement (“EULA”) applies to customers of John Snow Labs Inc. (as defined below), using any product of John Snow Labs Inc. on John Snow Labs Marketplace as defined below (hereinafter referred to “you”) and John Snow Labs Inc., a Delaware corporation (“John Snow Labs”, “we” or “us”).

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Description

The overall purpose of the joint FDA/USP (Food and Drug Administration/United States Pharmacopeia) Substance Registration System (SRS) is to support health information technology initiatives by generating UNIIs for substances in drugs, biologics, foods, and devices. The UNII (Unique Ingredient Identifier) is a non- proprietary, free, unique, unambiguous, non semantic, alphanumeric identifier based on a substance’s molecular structure and/or descriptive information. The procedures and management of the SRS are provided by the SRS Board. The SRS Board includes experts from both FDA and USP. The SRS operating procedures defined by the SRS Board are detailed in the SRS Manual.

The UNII is a core component of the US Federal Medication Terminology, it is used for product labeling, to assist in the generation of RxNorm, as an identifier for drug ingredients and allergens and in the future will be a component of the Environmental Protection Agency’s Substance Registry System. The UII is useful for understanding data contained in NLM’s (National Library of Medicine) Unified Medical Language System, National Cancer Institutes Enterprise Vocabulary Service, FDA Data Standards Council website, VA National Drug File Reference Terminology, FDA Inactive Ingredient Query Application and, proximately, USP Dictionary of USAN and International Drug Names.

About this Dataset

Data Info

Date Created

2007-03-20

Last Modified

2022-05-09

Version

2022-05-09

Update Frequency

Irregular

Temporal Coverage

N/A

Spatial Coverage

United States

Source

John Snow Labs; U.S. Food and Drug Administration (FDA), United States National Library of Medicine (NLM);

Source License URL

Source License Requirements

N/A

Source Citation

N/A

Keywords

FDA Product Code, UNII, SRS, FDA Registration System, FDA Database, Ingredient Search Results, Unique Ingredient Identifier Names, Unique Ingredient Identifier Records, UNII Descriptive Information, Drug Name Dictionary

Other Titles

Substance Registration System, UNII Records and Identifications

Data Fields

Name Description Type Constraints
Unique_Ingredient_IdentifierUNII (Unique Ingredient Identifier)stringrequired : 1unique : 1
Preferred_TermPreferred Term - Preferred Substance Name - display namestringrequired : 1
Registry_NumberRegistry Number used by many public chemical information systemsstring-
European_Chemicals_NumberEuropean Chemicals Agencies registry number (formerly known EINECS)string-
NCI_Thesaurus_CodeNCI Thesaurus Concept Codestring-
RXNORM_Ingredient_CodeRXNORM Ingredient Concept Codeintegerlevel : Nominal
PubChem_Compound_IdPubChem is a database of chemical molecules and their activities against biological assays.integerlevel : Nominal
ITIS_IdIntegrated Taxonomic Information System Taxonomic Serial Number (ITIS TSN)integerlevel : Nominal
NCBI_IdNCBI taxonomy organism IDintegerlevel : Nominal
USDA_Plants_IdUSDA PLANTS organism IDstring-
GRIN_IdUSDA Agricultural Research Service Germplasm Resources Information Network (GRIN) nomen IDintegerlevel : Nominal
MPNS_IdKew Gardens Medicinal Plants Name Service Record ID (includes source database prefix)string-
INN_IdSequential number assigned by World Health Organization's International Nonproprietary Name (INN) Programmeintegerlevel : Nominal
USAN_IDAlphanumeric code used by American Medical Association’s United States Adopted Names (USAN)string-
Molecular_FormulaMolecular Formula - total atoms represented as a molecular structure in a UNII descriptionstring-
INCHI_KeyA fixed-length string created from the IUPAC International Chemical Identifier (InChI)string-
SMILESSimplified Molecular-Input Line-Entry Systemstring-
UNII_TYPEUNII grouping based on intended role. Ionic Moiety UNIIs should not be used in the Ingredient Substance role because they are not charge-balanced, Molecular Fragment UNIIs should not be used in any listing role because they have unspecified atom attachments, Unspecified Ingredient UNIIs are imprecise. More precise Ingredient Substance or Specified Substance (ISO 11238) should be used instead.stringrequired : 1
UU_IDThe Food and Drug Administration Substance Registration System record IDstring-
Substance_TypeThe ISO 11238 substance type used for the primary substance identitystring-

Data Preview

Unique Ingredient IdentifierPreferred TermRegistry NumberEuropean Chemicals NumberNCI Thesaurus CodeRXNORM Ingredient CodePubChem Compound IdITIS IdNCBI IdUSDA Plants IdGRIN IdMPNS IdINN IdUSAN IDMolecular FormulaINCHI KeySMILESUNII TYPEUU IDSubstance Type
17462400.0CHF-6333 CATION1613620-10-276285164.0C27H28F3N6O3IHTRPSMRGYWUIM-HSZRJFAPSA-OCOC(=O)C1=C(C)N(C2=NNC(=O)N2[C@@H]1C3=CC=C(C=C3CC[N+](C)(C)C)C#N)C4=CC=CC(=C4)C(F)(F)FIONIC MOIETY4fdbca12-714b-4e79-a04f-459ba758813fchemical
129526470.05,8-DIMETHOXY(1,2,4)TRIAZOLO(1,5-C)PYRIMIDIN-2-AMINE219715-62-511446888.0C7H9N5O2DBJPBHJHAPAUQU-UHFFFAOYSA-NCOC1=CN=C(OC)N2N=C(N)N=C12INGREDIENT SUBSTANCEb1664dac-82e6-4b45-8321-7983531ccb46chemical
258808825.0MACROPIPER EXCELSUM LEAF130373.0INGREDIENT SUBSTANCEdfa0d3a4-00ab-4ce2-8ae3-9ab11462759estructurallyDiverse
377415922.0N-DESMETHYLVENLAFAXINE, (S)-392332-59-19860056.0C16H25NO2MKAFOJAJJMUXLW-OAHLLOKOSA-NCNC[C@H](C1=CC=C(OC)C=C1)C2(O)CCCCC2INGREDIENT SUBSTANCE1d47fe01-93d8-4009-8575-a75b05c586d5chemical
457970679.0VERRUCARIN54018-05-2INGREDIENT SUBSTANCEf60b3999-bccc-418c-92bc-07c486aecc4emixture
480546720.0HOMOCYCLOLEUCINE HYDROCHLORIDE39692-17-6254-594-32724466.0C7H13NO2.ClHGTKXSYHXQSKWNP-UHFFFAOYSA-NCl.NC1(CCCCC1)C(O)=OINGREDIENT SUBSTANCEbbf6e55f-f1cf-4cba-be17-4b7b5aa4085cchemical
503177591.0SUCCINALDEHYDE638-37-9211-333-812524.0C4H6O2PCSMJKASWLYICJ-UHFFFAOYSA-NO=CCCC=OINGREDIENT SUBSTANCE038d7ac4-9ac6-4189-921f-9a4e68e938e8chemical
909840846.0ALLIUM STRACHEYI WHOLE980680.0459419.0WCS-296682INGREDIENT SUBSTANCE2df5fddf-a897-4bd9-adce-bb40a4a3f1cbstructurallyDiverse
979361098.0OXALIS CORNICULATA LEAF29067.0212256.0OXCO26196.0WCSCMP-394644INGREDIENT SUBSTANCEdc80fbbd-11a8-4510-ada8-85953273c4b6structurallyDiverse
1521994599.0AURASPERONE D67924-64-5155008.0C31H24O10DVSATZLPJVYIRI-UHFFFAOYSA-NCOC1=CC(O)=C2C(O)=C3C(=O)C=C(C)OC3=C(C2=C1)C4=C(OC)C=C5C=C6OC(C)=CC(=O)C6=C(O)C5=C4OCINGREDIENT SUBSTANCE842f1aec-e75b-4c47-8d23-f8f7d435facfchemical